Refresh Plus Lubricant Eye Drops provides immediate, long lasting relief plus protection from dryness and irritation. Refresh Plus does more than just soothe and relive your eyes. It also protects against further irritation with its unique long lasting lubricant, CMS. Refresh Plus Lubricant Eye Drops is preservative-free to eliminate the potential irritation to your eyes caused by the preservatives found in some bottled eye drops. Safe to use as often as necessary. Refresh Plus provides 24-hour comfort for dry, irritated eyes.